In 2004, health technology assessment (HTA) was recognised as a ‘political priority’ by the EC and Council of Ministers, which led to a call to establish an effective and sustainable European network for HTA (EUnetHTA). The result was the establishment of the EUnetHTA Project in 2006. Since then, the work of this network for cross-border HTA cooperation within Europe has continued through various phases. The most innovative deliverable is the HTA Core Model® - a methodological framework that facilitates the production and sharing of HTA information. The current, Joint Action 2, phase of EUnetHTA aims to strengthen both the practical application of its tools and approaches to cross-border HTA collaboration, and to deliver recommendations on the implementation of a sustainable EUnetHTA.