Volume 21, Issue 4 - Obesity and Type 2 Diabetes

Is exercise physiology a real science?

Author: Donal J. O'Gorman

Abstract

Download the full article

References

1. O'Gorman DJ, Krook A. Exercise and the treatment of diabetes and obesity. Med Clin North Am 2011;95(5):953–69.
2. O'Gorman DJ, del Aguila LF, Williamson DL, Krishnan RK, Kirwan JP. Insulin and exercise differentially regulate IRS-1-associated PI3-kinase and glycogen synthase in human skeletal muscle during immediate recovery from exercise. J Appl Physiol 2000;89:1412–9.
3. Jessen N, Goodyear LJ. Contraction signaling to glucose transport in skeletal muscle. J Appl Physiol 2005;99:330–7.
4. Barrès R, Yan J, Egan B, Treebak JT, Rasmussen M, Fritz T, et al. Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metab 2012;15:405–11.
5. Booth FW, Chakravarthy MV, Gordon SE, et al. Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy. J Appl Physiol 2002;93:3–30.
6. Finck BN, Kelly DP. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 2006;116:615–22.
7. Bostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012;481:463–8.
8. Katzmarzyk PT. Physical activity, sedentary behavior, and health: paradigm paralysis or paradigm shift? Diabetes 2010;59:2717–25.
9. Cooper D, O'Gorman DJ. Exercise training has diverse responses in patients with type 2 diabetes. Diabetes Manag 2011;1(6):575–87.